• Psychiatrische Praxis · Aug 2012

    Comparative Study

    [Gender differences in response to CBT-orientated multimodal treatment in depressed patients with chronic pain].

    • Christoph Pieh, Jürgen Altmeppen, Susanne Neumeier, Thomas Loew, Michael Angerer, and Claas Lahmann.
    • Abteilung für Psychosomatische Medizin, Universitätsklinikum Regensburg. christoph.pieh@medbo.de
    • Psychiatr Prax. 2012 Aug 1;39(6):280-5.

    ObjectiveAlthough gender differences are increasingly the focus of current research, gender aspects in the response to pharmacological and non-pharmacological treatment of depression still remain unclear. The aim of this study was to analyze the impact of gender on the outcome of a CBT-orientated multimodal treatment in depressed outpatients with chronic pain.MethodsA total of 298 patients (154 women) underwent a standardized five-week CBT-orientated multimodal treatment. Depressive symptoms were measured at the beginning and end of the treatment with the German version of the Center for Epidemiological Studies Depression Scale (CES-D).ResultsThe improvement of depressive symptoms showed an effect size (ES) of 0.81 in the total sample. However, women improved considerably more (ES 0.96) than did men (ES 0.65) and these gender differences are seen in the complete sample (t = 2.757, df = 296, p = 0.006) as well as in the group without received antidepressants (t = 2.325, df = 151, p = 0.021).ConclusionWomen with a depressive disorder and chronic pain benefit significantly more from a CBT-orientated multimodal treatment and exhibit a considerably greater reduction of depressive symptoms than do men. These distinctions are not due to differences in received antidepressant medication, psychiatric comorbidities or educational background.© Georg Thieme Verlag KG Stuttgart · New York.

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