• Thromb Haemostasis · Jun 2007

    Multicenter Study

    Clinically suspected acute recurrent pulmonary embolism: a diagnostic challenge.

    • Mathilde Nijkeuter, Hanneke Kwakkel-van Erp, Maaike Söhne, Lidwine W Tick, Marieke J H A Kruip, Eric F Ullmann, Mark H H Kramer, Harry R Büller, Martin H Prins, Frank W G Leebeek, Menno V Huisman, and Christopher Study Investigators.
    • Department of General Internal Medicine- Endocrinology, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands. M.Nijkeuter@lumc.nl
    • Thromb Haemostasis. 2007 Jun 1;97(6):944-8.

    AbstractIt is unknown whether strategies validated for diagnosing pulmonary embolism (PE) are valid in patients with a history of PE. It was the objective of this study to investigate whether a diagnostic algorithm consisting of sequential application of a clinical decision rule (CDR), a quantitative D-dimer test and computed tomography (CT) safely ruled out a clinical suspicion of acute recurrent PE. Data were obtained from a diagnostic outcome study of patients suspected of PE. Acute recurrent PE was ruled out by an unlikely probability of PE (CDR score

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