• Arch. Dis. Child. · Apr 2008

    Multicenter Study

    Hyponatraemia and hypokalaemia during intravenous fluid administration.

    • K Armon, A Riordan, S Playfor, G Millman, A Khader, and Paediatric Research Society.
    • Norfolk and Norwich University Hospital NHS Trust, Colney Lane, Norwich, Norfolk NR4 7UY, UK. kate.armon@nnuh.nhs.uk
    • Arch. Dis. Child. 2008 Apr 1;93(4):285-7.

    BackgroundHospital-acquired hyponatraemia is associated with excessive volumes of hypotonic intravenous fluids and can cause death or permanent neurological deficit.MethodsA cross-sectional survey was carried out in 17 hospitals on all children receiving intravenous fluids during 1 day of a specified week in December 2004.Results77 of 99 children receiving intravenous fluids received hypotonic solutions and 38% received >105% of fluid requirements. 21 of 86 children were hyponatraemic, but the electrolytes of only 79% had been checked in the preceding 48 h.ConclusionsIntravenous fluids should be used with caution as regards the tonicity and volume administered, and with appropriate monitoring of serum electrolytes.

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