• Medicina · Jan 2011

    Review

    [Prophylactic treatment with antiepileptic drugs in neurological conditions].

    • Luciano A Sposato, Alfredo Thomson, Patricia M Riccio, Analia Calle, and Francisco R Klein.
    • Centro de Stroke, Instituto de Neurociencias de la Fundación Favaloro, Buenos Aires, Argentina. lucianosposato@gmail.com
    • Medicina (B Aires). 2011 Jan 1;71(1):73-7.

    AbstractProphylactic use of antiepileptic drugs in neurological conditions such as ischemic and hemorrhagic stroke, subarachnoid hemorrhage, head injury, and brain tumors has been matter of debate for many years. These drugs are used for reducing secondary neurological damage caused by epileptic seizures. However, the evidence supporting this indication is scarce. Potential drug interactions, side effects, and even neurotoxicity related to these drugs have raised concern about this therapeutic approach. In this review, we examine the evidence on the prophylactic use of antiepileptic drugs in the neurological disorders above mentioned.

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