• Scand J Thorac Cardiovasc Surg · Jan 1992

    Randomized Controlled Trial Clinical Trial

    Continuous extrapleural intercostal nerve block and post-thoracotomy pulmonary complications.

    • J Eng and S Sabanathan.
    • Department of Thoracic Surgery, Bradford Royal Infirmary, England.
    • Scand J Thorac Cardiovasc Surg. 1992 Jan 1;26(3):219-23.

    AbstractTo evaluate the effects of continuous extrapleural intercostal nerve block on post-thoracotomy pain and pulmonary complications, a randomized, double-blind, placebo-controlled study was conducted on 80 patients undergoing elective thoracotomy for pulmonary (n = 47) or oesophageal (n = 33) procedures. In patients who received continuous bupivacaine infusion, the requirement for intramuscular opiate and rectal diclofenac was less, the score on a visual linear analogue pain scale lower and recovery of pulmonary function more rapid than in saline-infused controls. Postoperative pulmonary complications occurred in 35% of the saline group, but only 10% of the patients with bupivacaine infusion (p < 0.01). In patients with chronic obstructive airways disease (COAD), the incidence of postoperative pulmonary complications was 54.5% in the saline group and only 4.5% in the bupivacaine group (p < 0.01). Among the patients without COAD there was no significant intergroup difference in such complications. We conclude that continuous extrapleural intercostal nerve block is effective for post-thoracotomy analgesia and reduces pulmonary complications of thoracotomy in patients with COAD.

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