• Jiagang Han, Zhenjun Wang, Guanghui Wei, Bingqiang Yi, Huachong Ma, Zhigang Gao, Yong Yang, Bo Zhao, Baocheng Zhao, and Yunlu Tao.
• Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China.
• Zhonghua Wai Ke Za Zhi. 2014 Jun 1;52(6):415-9.

ObjectiveTo investigate the incidence of surgical site infection (SSI) and risk factors in colorectal cancer surgery patients.MethodsBetween October 2003 and October 2013, 1 381 consecutive patients with colorectal cancer managed surgically with primary anastomosis were included in the study. There were 762 male and 619 female patients with mean body mass index (BMI) was (27.7 ± 3.7) kg/m², aged from 20 to 90 years with a median of 67 years. Patients undergoing emergency surgery and requiring stoma creation were excluded. The patients' characteristics, surgical conditions and prognosis were recorded. Univariate and multiple logistic regression analysis were used to identify any variable predictive factors of SSI.ResultsOne hundred twenty-six (9.12%) cases developed incisional SSI. The occurrence time for SSI was from 2 to 20 days, mean (6.7 ± 2.9) days. According to multivariable logistic regression analysis, BMI (OR = 1.058, P = 0.030), intraoperative contamination (OR = 10.549, P = 0.000) and open operation as compared with a laparoscopic procedure (OR = 2.111, P = 0.001) were significant independent predictors of incisional SSI. There was a significant decrease in incisional SSI in wound protectors group (OR = 1.646, P = 0.012).ConclusionBMI and intraoperative contamination are independent predictors of incisional SSI, and wound protectors and laparoscopic surgery are associated with a lower incidence of incisional SSI following colorectal cancer surgery.

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