• Acta Anaesthesiol Scand · Mar 1999

    Randomized Controlled Trial Clinical Trial

    Paracetamol 1 g given rectally at the end of minor gynaecological surgery is not efficacious in reducing postoperative pain.

    • A Hein, J Jakobsson, and G Ryberg.
    • Department of Anaesthesia, Karolinska Institute, Danderyds Hospital, Stockholm, Sweden.
    • Acta Anaesthesiol Scand. 1999 Mar 1;43(3):248-51.

    BackgroundWe studied the analgesic effects of 1 g paracetamol given rectally at the end of surgery in a prospective, randomised, double-blind study.MethodsOne hundred and forty ASA I-II women scheduled for elective termination of pregnancy under general anaesthesia were randomly allocated to receive paracetamol or placebo. All patients had standardised anaesthesia with propofol, fentanyl and oxygen in nitrous oxide. Postoperative pain was assessed by VAS score.ResultsWe could find no difference regarding postoperative pain, need for analgesics or time to discharge between the groups.ConclusionThe routine use of 1 g paracetamol given rectally at the end of surgery after termination of pregnancy seems not to be justified.

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