• Annual review of medicine · Jan 1996

    Review

    Goodpasture's disease and Alport's syndromes.

    • A N Turner and A J Rees.
    • Department of Medicine and Therapeutics, University of Aberdeen, Foresterhill, Scotland, United Kingdom.
    • Annu. Rev. Med. 1996 Jan 1;47:377-86.

    AbstractGoodpasture's, or anti-glomerular basement membrane, disease is an uncommon, usually severe disease caused by autoimmunity to a component of certain basement membranes. Alport's syndrome is an inherited, degenerative disorder that affects specific basement membranes. The two are linked by the involvement of type-IV collagen (basement membrane collagen) in their pathogenesis.

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