• Am J Hosp Palliat Care · Jan 2001

    Case Reports

    Methadone-induced myoclonus in advanced cancer.

    • N Sarhill, M P Davis, D Walsh, and C Nouneh.
    • Harry R. Horvitz Center for Palliative Medicine, Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, USA.
    • Am J Hosp Palliat Care. 2001 Jan 1;18(1):51-3.

    AbstractMethadone is recommended as being free of some of the neuropsychological side effects noticed with morphine, which are attributed to active metabolites. A patient that received methadone for cancer-associated pain developed myoclonus as a side effect. This has rarely been reported before in the literature. The pathophysiology and management of myoclonus are discussed.

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