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Case Reports
Lemierre's syndrome with double heterozygote status in the methylenetetrahydrofolate reductase gene.
- Mostafa Behpour-Oskooee, Abdollah Karimi, and Shirin Sayyahfar.
- Pediatric Infectious Diseases, Department of Pediatrics, Najmieh Hospital, Baghyatollah University of Medical Sciences, Tehran, Iran.
- World J Pediatr. 2014 Aug 1;10(3):281-3.
BackgroundThere are some risk factors being more vulnerable to Lemierre's syndrome such as a hypercoagulable state.MethodsWe report a rare case of Lemierre's syndrome with ethmoid and maxillary sinusitis, bilateral mastoiditis, and sigmoid sinus thrombosis.ResultsGenetic study revealed a double heterozygote status in the methylenetetrahydrofolate reductase gene including C677T and A1298C.ConclusionIt is suggested to screen patients with Lemierre's syndrome for a hypercoagulable state to consider anticoagulant therapy.
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