• Indian J Crit Care Med · Mar 2014

    Acute kidney injury in critically ill children: Risk factors and outcomes.

    • Shweta Naik, Jyoti Sharma, Rameshwor Yengkom, Vijay Kalrao, and Atul Mulay.
    • Department of Pediatrics, BVDUMC, Consultant Nephrologist, Viva Kidney Suraksha, Pune, Maharashtra, India.
    • Indian J Crit Care Med. 2014 Mar 1;18(3):129-33.

    BackgroundAcute kidney injury (AKI) is common in patients in the pediatric intensive care unit (PICU) and is associated with poor outcome. We conducted the present study to determine the incidence, risk factors and outcomes of AKI in the PICU.Materials And MethodsWe collected data retrospectively from case records of children admitted to the PICU during one year. We defined and classified AKI according to modified pRIFLE criteria. We used multivariate logistic regression to determine risk factors of AKI and association of AKI with mortality and morbidity.ResultsOf the 252 children included in the study, 103 (40.9%) children developed AKI. Of these 103 patients with AKI, 39 (37.9%) patients reached pRIFLE max of Risk, 37 (35.9%) patients reached Injury, and 27 (26.2%) had Failure. Mean Pediatric Risk of Mortality (PRISM III) score at admission was higher in patients with AKI than in controls (P < 0.001).

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