• Neurol Neurochir Pol · Jan 2001

    Clinical Trial Controlled Clinical Trial

    [Determination of melatonin concentrations in patients with consciousness disturbances after craniocerebral trauma. Preliminary communication].

    • I Gościński, A Dembińska-Kieć, M Krupa, A Zdzienicka, and M Moskała.
    • Kliniki Neurotraumatologii CM UJ w Krakowie.
    • Neurol Neurochir Pol. 2001 Jan 1;35(1):63-71.

    AbstractThe study was performed in cooperation of the Department of Neurotraumatology and the Department of Clinical Biochemistry Jagiellonian University in Cracow. In patients with central nervous system injury, diagnosed upon computerized tomography scan, melatonin levels were measured. The most frequent reason of damage was severe craniocerebral trauma. Consciousness, assessed according to Glasgow Coma Scale, was between 3 to 13 points. Melatonin levels were measured at 8 a.m. The investigation could not demonstrate any correlations between consciousness disturbances after head injury and serum melatonin levels in the morning. To draw a final conclusion further experiments are necessary. They will help to explain the role of endogenous melatonin in patients after craniocerebral injury.

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