• J Obstet Gynaecol · Jan 2016

    Randomized Controlled Trial

    Effect of lidocaine spray in pain management during office-based endometrial sampling: A randomised placebo-controlled trial.

    • H Aksoy, U Aksoy, S Ozyurt, G Acmaz, M A Babayigit, B Yücel, and T Aydin.
    • a Kayseri Military Hospital , Department of Obstetrics and Gynaecology , Kayseri , Turkey.
    • J Obstet Gynaecol. 2016 Jan 1; 36 (2): 246-50.

    AbstractOffice-based endometrial sampling is the most frequently performed gynaecological procedure. The procedure is usually associated with pain and discomfort. Several anaesthetic and analgesic techniques (e.g., non-steroidal anti-inflammatory drugs, paracervical block, misoprostol and topical anaesthetics) are used for pain management during endometrial sampling. There is no comprehensive study using lidocaine in spray form; we sought to investigate the analgesic efficacy of 10% lidocaine spray in patients undergoing office-based endometrial biopsy. We conducted a prospective, randomised (lidocaine spray (n = 60) and placebo (n = 60), respectively), double-blind study. The mean pain score during procedure was 3.51 ± 1.51 in the lidocaine spray group and 5.11 ± 1.66 in the placebo group. Lidocaine spray treatment significantly lowered the pain scores compared with placebo (p < 0.001). Lidocaine spray can be accepted as a non-invasive, easy to apply and more comfortable anaesthetic method for office-based endometrial sampling.

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