• Tuberc Respir Dis (Seoul) · Aug 2014

    Review

    Lung cancer screening: subsequent evidences of national lung screening trial.

    • Young Sik Park.
    • Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
    • Tuberc Respir Dis (Seoul). 2014 Aug 1;77(2):55-9.

    AbstractThe US National Lung Screening Trial (NLST) demonstrated a 20% reduction in lung cancer mortality and a 6.7% decrease in all-cause mortality. The NLST is the only trial showing positive results in a high-risk population, such as in patients with old age and heavy ever smokers. Lung cancer screening using a low-dose chest computed tomography might be beneficial for the high-risk group. However, there may also be potential adverse outcomes in terms of over diagnosis, bias and cost-effectiveness. Until now, lung cancer screening remains controversial. In this review, we wish to discuss the evolution of lung cancer screening and summarize existing evidences and recommendations.

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