• Infect. Dis. Clin. North Am. · Dec 2009

    Review

    Use of antibacterial agents in renal failure.

    • Brett Gilbert, Paul Robbins, and Lawrence L Livornese.
    • Division of Infectious Diseases, Department of Medicine, Thomas, Jefferson University Hospital, Lankenau Hospital, Lankenau Medical Building, Suite 164, Wynnewood, PA 19096, USA. santorow@mlhs.org
    • Infect. Dis. Clin. North Am. 2009 Dec 1;23(4):899-924, viii.

    AbstractThis article provides background information on the pharmacokinetics of antibacterial agents in patients who have normal and impaired renal function. Tables are provided to allow quick determination of appropriate dosages for varying degrees of renal failure. The use of serum levels; newer strategies for cefazolin, vancomycin and aminoglycoside dosing; methods of dialysis and associated antibiotics dosage adjustments, and antibiotic toxicity in renal failure are reviewed.

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