Arterial desaturation during induction in healthy adults:

Anaesth Intensive Care · May 1991

Randomized Controlled Trial Comparative Study Clinical Trial

Arterial desaturation during induction in healthy adults: should preoxygenation be a routine?

We studied the haemoglobin saturation of one hundred healthy patients equally divided into two groups. Group 1 patients received three minutes of preoxygenation prior to thiopentone induction followed by inhalational anaesthetics. ⋯ None of the patients in Group 1 showed any arterial oxygen desaturation during the five minutes of the induction period, whereas 21 patients in Group 2 showed definite desaturation (P less than 0.005), of which fifteen patients had a saturation of 90% or less (P less than 0.005) and six had a saturation of 85% or less. Since those were healthy patients and the anaesthetics were given by experienced anaesthetists, we concluded that some form of preoxygenation should be used in all patients receiving general anaesthesia.

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- M C Kung, C T Hung, K P Ng, T K Au, R Lo, and A Lam.
- Department of Anaesthesia, Queen Elizabeth Hospital, Hong Kong.
- Anaesth Intensive Care. 1991 May 1;19(2):192-6.
AbstractWe studied the haemoglobin saturation of one hundred healthy patients equally divided into two groups. Group 1 patients received three minutes of preoxygenation prior to thiopentone induction followed by inhalational anaesthetics. Group 2 patients breathed room air prior to induction. None of the patients in Group 1 showed any arterial oxygen desaturation during the five minutes of the induction period, whereas 21 patients in Group 2 showed definite desaturation (P less than 0.005), of which fifteen patients had a saturation of 90% or less (P less than 0.005) and six had a saturation of 85% or less. Since those were healthy patients and the anaesthetics were given by experienced anaesthetists, we concluded that some form of preoxygenation should be used in all patients receiving general anaesthesia.

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Arterial desaturation during induction in healthy adults: should preoxygenation be a routine?

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