• Emerg. Med. Clin. North Am. · Aug 2014

    Review

    Myeloproliferative Disorders.

    • John H Burton and Brian Meier.
    • Department of Emergency Medicine, Carilion Clinic, 525 Janette Avenue Southwest, Roanoke, VA 24016, USA.
    • Emerg. Med. Clin. North Am.. 2014 Aug 1;32(3):597-612.

    AbstractThe emergency providers generally encounters myeloproliferative disorders (MPNs) in 1 of 2 ways: as striking laboratory abnormalities of seeming unknown consequence, or in previously diagnosed patients presenting with complications. The course of patients with MPNs is highly variable, but major complications can arise. Emergent conditions related to hyperviscosity need to be recognized early and treated aggressively. Rapid hydration, transfusion, cytoreduction, and early hematology consultation can be lifesaving. Likewise, although management is not altered, a high index of suspicion for thrombotic complications is required in patients with known MPNs as these are a significant cause of morbidity and mortality.Copyright © 2014 Elsevier Inc. All rights reserved.

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