• Klinische Wochenschrift · Dec 1991

    Review

    Role of iron and oxygen radicals in hemorrhage and shock.

    • B E Hedlund and P E Hallaway.
    • Biomedical Frontiers Inc., Minneapolis.
    • Klin. Wochenschr. 1991 Dec 15;69(21-23):1113-7.

    AbstractThis contribution focuses on the role of iron as a critical component in the genesis of oxygen radical mediated tissue injury occurring after global ischemia associated with severe hypovolemic shock. Conventional colloid or crystalloid fluid resuscitation does not adequately protect organs susceptible to reperfusion injury. One approach aimed at attenuating such post-trauma reperfusion injury is systemic, high dose, iron chelation used in combination with colloid fluid replacement.

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