• J. Infect. Chemother. · Feb 2010

    Administration of neuraminidase inhibitors for the treatment of Japanese patients infected with the novel influenza A (H1N1).

    • Kenji Ohnishi and Fukumi Nakamura-Uchiyama.
    • Department of Infectious Diseases, Tokyo Metropolitan Bokutoh General Hospital, Tokyo, Japan. infection@bokutoh-hp.metro.tokyo.jp
    • J. Infect. Chemother. 2010 Feb 1;16(1):62-3.

    AbstractThe Centers for Disease Control and Prevention in the United States recommend the use of neuraminidase inhibitors for treating the novel influenza A (H1N1) in patients requiring desirable antiviral agents. However, the efficacy and side effects of neuraminidase inhibitors in Japanese patients infected with the novel influenza A (H1N1) are not well known. It is worth reporting on the results of the administration of neuraminidase inhibitors in Japanese patients infected with the novel influenza A (H1N1), as it is believed the number of Japanese patients will increase in the future. We treated seven Japanese patients (five adults and two juveniles) infected with the novel influenza A (H1N1) with oseltamivir and zanamivir, and good clinical courses were obtained. Our study indicates that oseltamivir and zanamivir may indeed be useful in Japanese patients infected with the novel influenza A (H1N1) in cases where antiviral therapy is required.

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