• Otolaryngol Head Neck Surg · Feb 2008

    Randomized Controlled Trial Comparative Study

    The effect of anesthetic agents on perioperative bleeding during tonsillectomy: propofol-based versus desflurane-based anesthesia.

    • Semsettin Okuyucu, Kerem Inanoglu, Cagla Ozbakis Akkurt, Ertap Akoglu, and Safak Dagli.
    • Department of Otolaryngology, Mustafa Kemal University Medical Faculty, Antakya, Hatay, Turkey. semsettinokuyucu@yahoo.com <semsettinokuyucu@yahoo.com>
    • Otolaryngol Head Neck Surg. 2008 Feb 1;138(2):158-61.

    ObjectiveHemorrhage during tonsillectomy is related to the surgical technique, management of bleeding, and choice of anesthetic agent. This study evaluated the effects of anesthetic agents on hemorrhage during tonsillectomy with standardized surgical techniques and management of bleeding.Study DesignDouble-blind, randomized controlled trial.Subjects And MethodsSixty patients, aged 3 to 12 years, who were scheduled for elective tonsillectomy were enrolled in the study. Propofol-based anesthesia was administered to the first group; desflurane-based anesthesia, to the second. The amount of blood loss due to hemorrhage was measured.ResultsPropofol-based anesthesia significantly decreased bleeding during tonsillectomy.ConclusionPropofol-based anesthesia is a reliable method for use in children who undergo tonsillectomy.

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