• Presse Med · Jan 1999

    Review

    [Organ procurement from cardiac arrest donors: outcome of kidney grafts and recommendations].

    • G Benoit, A Decaux, P Eschwège, A Descorps Declere, P Moine, P Blanchet, F Coulomb, F Brivet, J Decaris, L Joseph, D Devictor, C Richard, C Gillot, and G Huault.
    • Service d'Urologie, Université Paris Sud, Le Kremlin-Bicêtre.
    • Presse Med. 1999 Jan 9;28(1):3-7.

    ObjectivesTo compare literature data with results obtained with organs procured from donors who died from cardiac arrest and to make proposals for this mode of organ procurement in France.MethodsOver the last 10 years, 10 organ donors (2%) among a series of 486 donors in a state of brain death, had died of cardiac arrest. The arrest were perfused with double-balloon catheters. The outcome of the subsequent kidney grafts was compared with data in the literature.ResultsFifteen of the 18 kidneys from cardiac arrest donors were functioning 1 month after implantation compared with 17 of the 20 kidneys from braindeath donors with beating hearts. The rate of acute tubular necrosis was 55% in the cardiac arrest kidneys and 40% in the beating-heart kidneys. Serum creatinine at 1 yeart was 145 +/- 69 mumol/l 17 +/- 29 mumol/l respectively.DiscussionThese results and those reported in the literature demonstrate that kidney procurement from cardiac arrest donors is feasible. If intensive care and surgery units are well organized, this type of organ procurement could provide a larger number of organs for transplantation. Emergency teams must be available for preparing and transferring the organs.

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