• Cochrane Db Syst Rev · Jan 2005

    Review Meta Analysis

    Action plans for chronic obstructive pulmonary disease.

    • A C Turnock, E H Walters, J A E Walters, and R Wood-Baker.
    • University of Tasmania Medical School, Discipline of Medicine, University of Tasmania, 43 Collins Street, Hobart, Tasmania, Australia 7001. aturnock@utas.edu.au
    • Cochrane Db Syst Rev. 2005 Jan 1(4):CD005074.

    BackgroundThe effectiveness of action plans as treatment for chronic obstructive pulmonary disease (COPD) is not known.ObjectivesTo assess the efficacy of action plans in the management of COPD.Search StrategyWe searched the Cochrane Airways Group Specialised Register, CENTRAL, MEDLINE, CINAHL and the National Research Register of Ongoing Trials. We also searched reference lists of identified studies. The search was completed in August 2004.Selection CriteriaRandomised controlled trials of action plans in COPD. Studies with a primary diagnosis of asthma excluded.Data Collection And AnalysisTwo reviewers independently assessed trial quality and extracted data. Investigators were contacted for additional information when necessary. Study results were combined in meta-analyses using the Cochrane Collaboration software RevMan.Main ResultsThere was evidence of a positive effect of action plans on self-management knowledge. The mean difference (MD) for recognition of a severe exacerbation was 2.50; 95% confidence interval 1.04 to 3.96, for self-action in severe exacerbations MD 1.50; 95% confidence interval 0.62 to 2.38 and the use of antibiotics MD 6.00; 95% confidence interval 2.68 to 9.32. There was also evidence of a positive effect on the initiation of antibiotics (odds ratio (OR) 10.16; 95% confidence interval 2.02 to 51.09) and/or oral steroids (OR 6.58; 95% confidence interval 1.29 to 33.62). However, there was no evidence of significant effects on healthcare utilisation, health-related quality of life, lung function, functional capacity, symptom scores, mortality, anxiety, or depression. No trials used as outcomes: number of exacerbations, length of exacerbations, or days lost from work.Authors' ConclusionsThis review shows there is evidence that action plans aid people with COPD in recognising and reacting appropriately to an exacerbation of their symptoms via the self-initiation of antibiotics or steroids. Further research needs to be completed with more comprehensive outcomes measures in order to ascertain whether this results in significantly decreased morbidity and/or mortality.

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