• Autoimmunity reviews · Dec 2012

    Review

    Exercise as a therapeutic tool to counteract inflammation and clinical symptoms in autoimmune rheumatic diseases.

    • Luiz Augusto Perandini, Ana Lúcia de Sá-Pinto, Hamilton Roschel, Fabiana Braga Benatti, Fernanda Rodrigues Lima, Eloisa Bonfá, and Bruno Gualano.
    • Rheumatology Division, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
    • Autoimmun Rev. 2012 Dec 1;12(2):218-24.

    AbstractChronic inflammation is a common feature shared by several autoimmune rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus, idiopathic inflammatory myopathies, systemic sclerosis, and ankylosing spondylitis. Therefore, blocking or reducing inflammation is one of the major treatment strategies in these diseases. In this context, exercise training has emerged as a potential therapeutic tool in counteracting systemic inflammation, thereby leading to better clinical outcomes. The aims of this review are i) to provide a summary of the clinical effects of exercise training in selected autoimmune rheumatic diseases; and ii) to discuss the potential anti-inflammatory role of exercise training in autoimmune rheumatic diseases, stressing the gaps in literature and the clinical and scientific perspectives in the field.Copyright © 2012 Elsevier B.V. All rights reserved.

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