• Internal medicine · May 1995

    Case Reports

    Effect of octreotide on ventilation and dyspnea sensation in a patient with cirrhotic hypoxemia.

    • S Kobayashi, M Nishimura, H Taguchi, K Miyamoto, and Y Kawakami.
    • First Department of Internal Medicine, School of Medicine, Hokkaido University, Sapporo.
    • Intern. Med. 1995 May 1;34(5):401-5.

    AbstractWe examined the long-term effects of octreotide, a somatostatin analogue, on ventilation in a case of cirrhotic hypoxemia. After daily administration of octreotide for one month, the dyspnea on exertion was notably ameliorated, although pulmonary gas exchange was only slightly improved. The octreotide therapy reduced the hypoxic ventilatory drive, which may be one reason for the relief of the dyspnea sensation.

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