• Clin. Microbiol. Infect. · Oct 2012

    Multicenter Study

    Mucormycosis after allogeneic haematopoietic stem cell transplantation: a French Multicentre Cohort Study (2003-2008).

    • A Xhaard, F Lanternier, R Porcher, E Dannaoui, A Bergeron, L Clement, C Lacroix, R Herbrecht, F Legrand, M Mohty, M Michallet, C Cordonnier, S Malak, D Guyotat, L J Couderc, G Socié, N Milpied, O Lortholary, and P Ribaud.
    • Service d'Hématologie- Greffe, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France. alienor.xhaard@sls.aphp.fr
    • Clin. Microbiol. Infect. 2012 Oct 1;18(10):E396-400.

    AbstractWe conducted a nationwide retrospective study to evaluate clinical characteristics and outcome of mucormycosis among allogeneic haematopoietic stem cell transplant recipients. Twenty-nine patients were diagnosed between 2003 and 2008. Mucormycosis occurred at a median of 225 days after allogeneic haematopoietic stem cell transplant, and as a breakthrough infection in 23 cases. Twenty-six patients were receiving steroids, mainly for graft-versus-host disease treatment, while ten had experienced a prior post-transplant invasive fungal infection. Twenty-six patients received an antifungal treatment; surgery was performed in 12. Overall survival was 34% at 3 months and 17% at 1 year.© 2012 The Authors. Clinical Microbiology and Infection © 2012 European Society of Clinical Microbiology and Infectious Diseases.

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