• Christiane Mattusch, Klaus-Werner Diederich, Andrej Schmidt, Dierk Scheinert, Holger Thiele, Gerhard Schuler, and Steffen Desch.
• University of Leipzig-Heart Center, Department of Internal Medicine/Cardiology, Germany.
• Angiology. 2011 Jul 1;62(5):376-80.

AbstractSerum levels of S-100B and neurone-specific enolase (NSE) reflect cerebral injury in a variety of neurological conditions such as stroke, traumatic brain injury, and cardiac arrest. There are limited data on the release of S-100B and NSE following carotid artery stenting (CAS). In 22 patients undergoing CAS, serial blood samples for S-100B and NSE were collected before and 2, 4, and 6 to 8 hours after the procedure. A group of 20 patients with significant CAS undergoing purely diagnostic angiography served as controls. A significant increase in S-100B levels was observed 2 hours after the procedure in patients with CAS (P = .001) with a gradual decline over the next hours. In contrast, patients who underwent purely diagnostic angiography did not show significant changes in S-100B levels up to 8 hours after the procedure. Neither patients with CAS nor those undergoing diagnostic angiography displayed any significant changes in serial NSE levels.

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