-
Randomized Controlled Trial Comparative Study Clinical Trial
Treatment of renal colic by prostaglandin synthetase inhibitors and avafortan (analgesic antispasmodic).
- A E el-Sherif, R Foda, L J Norlen, and H Yahia.
- Department of Urology, Hamad General Hospital, Doha, Qatar.
- Br J Urol. 1990 Dec 1;66(6):602-5.
AbstractIn a study of the pain-relieving effect of 3 drugs commonly used to treat acute renal colic in this hospital, intravenous indomethacin and intramuscular diclofenac (prostaglandin synthetase inhibitors) were compared with intravenous Avafortan (analgesic antispasmodic). As first-line analgesics, prostaglandin synthetase inhibitors, if given intravenously, offer an effective alternative to Avafortan. Of 145 patients studied, 32 required a second injection for complete relief of pain. Administering a second dose of prostaglandin synthetase inhibitors resulted in equally significant pain relief rate even though the route was intramuscular.
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