• J Clin Neurosci · Jan 2007

    Case Reports

    Malignant transformation of high-grade astrocytoma associated with neurocysticercosis in a patient with Turcot syndrome.

    • Kuniyasu Niizuma, Miki Fujimura, Toshihiro Kumabe, and Tominaga Tominaga.
    • Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
    • J Clin Neurosci. 2007 Jan 1;14(1):53-5.

    AbstractA 45-year-old woman with anaplastic astrocytoma was clinically diagnosed with Turcot syndrome, and subsequently developed simultaneous neurocysticercosis and malignant transformation to glioblastoma. The parasitic cysts and glioblastoma were microsurgically removed. Histological examination of surgical specimens revealed neurocysticercosis between the normal brain tissue and glioblastoma. The clinical course and histological findings suggest that the parasitic infection and/or genetic changes contributed to the malignant transformation of the astrocytic tumour.

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