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Clinical biochemistry · Nov 2005
NT-proBNP in the differential diagnosis of acute dyspnea in the emergency department.
- Martina Zaninotto, Monica Mion, Sara Altinier, Mara Pastorello, Stefano Rocco, Franco Tosato, Sabino Iliceto, and Mario Plebani.
- Department of Laboratory Medicine, University-Hospital, Padova, Italy.
- Clin. Biochem. 2005 Nov 1;38(11):1041-4.
ObjectivesThe purpose of this study was to verify the usefulness of NT-proBNP in the differential diagnosis of dyspnea in a population of patients presenting in the ER with breathlessness.Design And MethodsIn samples from 122 patients presenting in the ER with acute-severe dyspnea and from 25 subjects enrolled as a "comparison group" (NORM), NT-proBNP levels were measured. Patients have been classified on the basis of discharge diagnosis: pulmonary disease (PD, n = 23), pulmonary concomitant to cardiac disease (MIXED, n = 17), pulmonary embolism (EMB, n = 8), cardiac disease (CARD, n = 56), acute myocardial infarction (AMI, n = 11) and other disease (OTHER, n = 7).ResultsA significant difference in NT-proBNP values (P
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