• Hyun Kang, Su-Man Cha, Sun-Gyoo Park, Yong-Hun Jung, Young-Cheol Woo, Jin-Yun Kim, Gill-Hoi Koo, Seong-Deok Kim, and Chong-Wha Baek.
• Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul 156-576, Republic of Korea.
• Acta Med Okayama. 2010 Oct 1;64(5):307-16.

AbstractIt is not known whether changing from isoflurane to desflurane during the latter part of anesthesia shows early emergence and recovery in long surgery. We therefore evaluated the effects of changing isoflurane to desflurane on emergence and recovery. Eighty-two patients were randomly assigned to receive isoflurane (Group I) or desflurane (Group D) or to change from isoflurane to desflurane anesthesia (Group X). At the point when there was an hour until the operation would end, isoflurane was replaced with 1 MAC of desflurane in Group X, and isoflurane and desflurane were maintained at 1 MAC in Groups I and D. When the operation ended, we compared the emergence and recovery characteristics among the 3 groups. Compared with Group I, Group X showed faster emergence and recovery. Group X and Group D showed similar emergence and recovery. In conclusion, changing isoflurane to desflurane during the latter part of anesthesia improves emergence and recovery.

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