• Acta Anaesthesiol Belg · Jan 1996

    Randomized Controlled Trial Clinical Trial

    Carboxyhemoglobin concentrations during desflurane and isoflurane closed-circuit anesthesia.

    • J F Hendrickx, M Soetens, M De Vel, P Van der Aa, and A M De Wolf.
    • Department of Anesthesiology and Critical Care Medicine, University of Pittsburgh School of Medicine, Pennsylvania, USA.
    • Acta Anaesthesiol Belg. 1996 Jan 1;47(2):67-72.

    AbstractDesflurane has been implicated in carbon monoxide (CO) intoxication during general anesthesia under certain circumstances. Carboxyhemoglobin (COHb) concentrations were determined in forty-one patients who were randomly allocated to receive closed-circuit anesthesia (CCA) with 1.3 MAC of desflurane (n = 21) or isoflurane (n = 20) in oxygen. Soda lime was used to bind the produced CO2 in previous anesthetic procedures with fresh gas flows of < 21/min. In the desflurane group, COHb concentrations (mean +/- SD) were 0.86 +/- 1.15% and 0.81 +/- 1.11% before and after 1 h of anesthesia, respectively. In the isoflurane group, COHb concentrations were 1.15 +/- 1.47% and 1.19 +/- 1.39% before and after 1 h of anesthesia, respectively. COHb concentrations did not increase after 2 h of CCA in seven patients. Our data suggest that closed-circuit anesthesia with desflurane or isoflurane does not produce clinically significant increases in COHb concentrations under conditions that allow the soda lime to remain sufficiently wet.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…