• Anaesth Intensive Care · Aug 1989

    Comparative Study Clinical Trial Controlled Clinical Trial

    Interpleural administration of bupivacaine after cholecystectomy: a comparison with intercostal nerve block.

    • D W Blake, G Donnan, and J Novella.
    • Department of Anaesthesia, Prince Henry's Hospital, Melbourne, Australia.
    • Anaesth Intensive Care. 1989 Aug 1;17(3):269-74.

    AbstractPethidine requirements and verbal pain scores were recorded in 36 patients after cholecystectomy via subcostal incision. All patients also received 20 ml 0.5% bupivacaine with adrenaline 1/200,000. Group 1 (12 patients) received unilateral intercostal nerve blocks. Interpleural catheters were inserted through the 8th intercostal space in the remaining patients; 12 received local anaesthetic via the catheter immediately after surgery (Group 2) and 12 were given local anaesthetic at three hours (Group 3). Small asymptomatic pneumothoraces were noted on chest X-ray in six of the 24 patients with interpleural catheters. Both types of local anaesthesia produced lower pain scores than pethidine alone (P less than 0.05) with 25% of intercostal nerve blocks and 63% of interpleural catheters requiring no pethidine in the following three hours. The provision of catheter 'top-ups' between six and 18 hours after surgery also resulted in lower pain scores and a reduction in pethidine requirements (P less than 0.05).

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