• J. Clin. Microbiol. · Aug 2006

    Evaluation of the GenoType Mycobacteria Direct assay for detection of Mycobacterium tuberculosis complex and four atypical mycobacterial species in clinical samples.

    • F Franco-Alvarez de Luna, P Ruiz, J Gutiérrez, and M Casal.
    • Microbiology Service, Reina Sofia University Hospital, and Mycobacteria Reference Center, Faculty of Medicine, Cordoba University, Cordoba, Spain.
    • J. Clin. Microbiol. 2006 Aug 1;44(8):3025-7.

    AbstractWe evaluated GenoType Mycobacteria Direct (GTMD), a novel commercial assay based on nucleic acid sequence-based amplification technology, for the detection of Mycobacterium tuberculosis complex, M. avium, M. intracellulare, M. kansasii, and M. malmoense directly from clinical specimens. A total of 134 respiratory and extrapulmonary samples from 65 patients were processed. Sensitivity, specificity, positive predictive, and negative predictive values for GTMD were 92, 100, 100, and 77%, respectively. The GMTD technique is useful, reliable, and rapid when used during the normal routine of a clinical laboratory.

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