• Mult. Scler. · Nov 2011

    Case Reports

    Contact dermatitis induced by glatiramer acetate.

    • S Haltmeier, M Yildiz, S Müller, M D Anliker, and L Heinzerling.
    • Department of Dermatology and Allergy, Cantonal Hospital of St Gallen, Switzerland. susannehaltmeier@gmx.net
    • Mult. Scler. 2011 Nov 1;17(11):1390-2.

    AbstractGlatiramer acetate (Copaxone(®)) is an immunomodulatory polypeptide used in patients with relapsing-remitting multiple sclerosis. It represents a safe treatment option with mild side effects. In this study, we look at a 39-year-old woman who received glatiramer acetate as subcutaneous injections for two months and developed contact dermatitis. The drug had to be stopped, and treatment with topical prednisone was initiated. Prick/scratch testing was negative but the lymphocyte transformation test was highly positive for glatiramer acetate. This is the first report on contact dermatitis induced by glatiramer acetate injections. The treatment consisted of local topical steroids and cessation of the drug.

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