• J. Clin. Microbiol. · May 2008

    Agammaglobulinemia and Staphylococcus aureus botryomycosis in a cohort of related sentinel Swiss Webster mice.

    • Erin C Bridgeford, James G Fox, Prashant R Nambiar, and Arlin B Rogers.
    • Division of Comparative Medicine 16-825, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. ecbridge@mit.edu
    • J. Clin. Microbiol. 2008 May 1;46(5):1881-4.

    AbstractSentinel mouse seroconversion to infectious agents is critical for laboratory animal facility disease monitoring. We report spontaneous emergence of non-sex-linked agammaglobulinemia with B-cell deficiency and cutaneous Staphylococcus aureus granulomatosis (botryomycosis) in a cohort of related Swiss Webster sentinel mice. Our experience reinforces the importance of immunocompetency validation in surveillance programs.

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