• Nicholas G Wysham, Amy P Abernethy, and Christopher E Cox.
• aDivision of Pulmonary and Critical Care Medicine, Department of Medicine bCenter for Learning Healthcare cDivision of Medical Oncology, Department of Medicine dProgram to Support People and Enhance Recovery, Duke University, Durham, North Carolina, USA.
• Curr Opin Crit Care. 2014 Oct 1; 20 (5): 566-72.

Purpose Of ReviewPrediction models in critical illness are generally limited to short-term mortality and uncommonly include patient-centered outcomes. Current outcome prediction tools are also insensitive to individual context or evolution in healthcare practice, potentially limiting their value over time. Improved prognostication of patient-centered outcomes in critical illness could enhance decision-making quality in the ICU.Recent FindingsPatient-reported outcomes have emerged as precise methodological measures of patient-centered variables and have been successfully employed using diverse platforms and technologies, enhancing the value of research in critical illness survivorship and in direct patient care. The learning health system is an emerging ideal characterized by integration of multiple data sources into a smart and interconnected health information technology infrastructure with the goal of rapidly optimizing patient care. We propose a vision of a smart, interconnected learning health system with integrated electronic patient-reported outcomes to optimize patient-centered care, including critical care outcome prediction.SummaryA learning health system infrastructure integrating electronic patient-reported outcomes may aid in the management of critical illness-associated conditions and yield tools to improve prognostication of patient-centered outcomes in critical illness.

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