• Jpen Parenter Enter · Jan 1986

    Case Reports

    Shoshin beriberi: an unusual complication of prolonged parenteral nutrition.

    • P La Selve, P Demolin, L Holzapfel, P L Blanc, G Teyssier, and D Robert.
    • Jpen Parenter Enter. 1986 Jan 1;10(1):102-3.

    AbstractAfter 4 weeks of total parenteral nutrition (TPN), a 12-yr-old girl exhibited an acute heart failure with high cardiac output, anuria, and severe lactic acidosis. The clinical, hemodynamic, and biological data suggested the diagnosis of shoshin beriberi which was proved by the low erythrocyte transketolase activity with elevated "TPP effect" and by the dramatic improvement of the patient after thiamin administration. Thiamin deficiency and severe neurological disorders have been described during long-term parenteral nutrition. To our knowledge, this is the first report of the cardiovascular complication of this vitamin deprivation in long-term TPN.

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