• Anaesthesia · Jan 1996

    Uptake of desflurane during anaesthesia.

    • T J Walker, M K Chakrabarti, and G G Lockwood.
    • Department of Anaesthesia, Hammersmith Hospital, London.
    • Anaesthesia. 1996 Jan 1;51(1):33-36.

    AbstractThe amount of desflurane required to maintain an end-expired concentration of 8% was measured in 30 ASA 1 and 2 patients undergoing elective spinal surgery. The anaesthetic was administered using a computer-controlled closed circle system. After an initial period during which the expired concentration of desflurane was stabilised (4 min) the rate of uptake showed a bi-exponential decline. Mean cumulative usage of desflurane was 10.1 ml of liquid at 30 min, 14.8 ml at 60 min, 25.4 ml at 120 min, 35.8 at 180 min.

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