• Renée J Detollenaere, Jan den Boon, Mark E Vierhout, and Hugo W F van Eijndhoven.
• Isala klinieken, afd. Gynaecologie en Verloskunde, Zwolle, the Netherlands. r.j.detollenaere@isala.nl
• Ned Tijdschr Geneeskd. 2011 Jan 1;155(42):A3623.

ObjectiveTo compare the outcomes of uterus preserving procedures and vaginal hysterectomy in treatment of uterine prolapse.DesignSystematic review.MethodWe searched in Pubmed, Embase, the Cochrane Library and the reference lists of relevant publications for articles comparing uterus preserving procedures with vaginal hysterectomy. The following outcome measures were studied: anatomical result, subjective outcome regarding prolapse symptoms, micturition, defecation and sexual function, quality of life, duration of surgery, duration of hospital stay, amount of blood loss, complications and postoperative recovery.ResultsWe found one systematic review, one randomised trial and five cohort studies, from which eight comparative studies were selected for review. There was no difference in subjective outcome after sacrospinous fixation, Manchester Fothergill procedure, abdominal hysteropexy and intravaginal slingplasty on comparison with vaginal hysterectomy. All procedures, except for sacrospinous ligament fixation, had similar anatomical outcomes to vaginal hysterectomy. With the exception of Manchester Fothergill procedure hospital stay was shorter after uterus preservation. The quality of most of the studies was poor, with only small numbers of patients included and short-term follow up.ConclusionsAlthough some uterus preserving procedures are associated with shorter operation time, shorter duration of hospital stay and less blood loss than vaginal hysterectomy, based on the current literature there is no clear preference for either uterus preserving surgery or hysterectomy in surgical treatment of uterine descent, since randomised trials of sufficient quality are lacking. Prospective clinical randomised trials with long term follow-up are needed to investigate the value of uterine preserving procedures.

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