• Yasuo Okumura, Ichiro Watanabe, Masayoshi Kofune, Koichi Nagashima, Kazumasa Sonoda, Hiroaki Mano, Kimie Ohkubo, Toshiko Nakai, Naoko Sasaki, Rikitake Kogawa, Ayako Maruyama, and Atsushi Hirayama.
• Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan. yasuwo128@yahoo.co.jp
• J. Cardiovasc. Electrophysiol. 2013 Mar 1;24(3):259-66.

UnlabelledAnatomic Distortion of 3D Mapping. BackgroundAlthough catheter tip-tissue contact is known as a reliable basis for mapping and ablation of atrial fibrillation (AF), the effects of different mapping methods on 3-dimensional (3D) map configuration remain unknown.Methods And ResultsTwenty AF patients underwent Carto-based 3D ultrasound (US) evaluation. Left atrium (LA)/pulmonary vein (PV) geometry was constructed with the 3D US system. The resulting geometry was compared to geometries created with a fast electroanatomical mapping (FAM) algorithm and 3D US merged with computed tomography (merged 3D US-CT). The 3D US-derived LA volumes were smaller than the FAM- and merged 3D US-CT-derived volumes (75 ± 21 cm(3) vs 120 ± 20 cm(3) and 125 ± 25 cm(3) , P < 0.0001 for both). Differences in anatomic PV orifice fiducials between 3D US- and FAM- and merged 3D US-CT-derived geometries were 6.0 (interquartile range 0-9.3) mm and 4.1 (0-7.0) mm, respectively. Extensive encircling PV isolation guided by 3D US images with real-time 2D intracardiac echocardiography-based visualization of catheter tip-tissue contact generated ablation point (n = 983) drop-out at 1.9 ± 3.8 mm beyond the surface of the 3D US-derived LA/PV geometry. However, these same points were located 1.5 ± 5.4 and 0.4 ± 4.1 mm below the FAM- and merged 3D US-CT-derived surfaces.ConclusionsDifferent mapping methods yield different 3D geometries. When AF ablation is guided by 3D US-derived images, ablation points fall beyond the 3D US surface but below the FAM- or merged 3D US-CT-derived surface. Our data reveal anatomic distortion of 3D images, providing important information for improving the safety and efficacy of 3D mapping-guided AF ablation. (J Cardiovasc Electrophysiol, Vol. 24, pp. 259-266, March 2013).© 2012 Wiley Periodicals, Inc.

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