• J Clin Psychiatry · Nov 2014

    Meta Analysis

    The effects of mind-body interventions on sleep in cancer patients: a meta-analysis of randomized controlled trials.

    • Hsiao-Yean Chiu, Pei-Chuan Chiang, Nae-Fang Miao, En-Yuan Lin, and Pei-Shan Tsai.
    • Graduate Institute of Nursing, College of Nursing, Taipei Medical University, Taipei.
    • J Clin Psychiatry. 2014 Nov 1;75(11):1215-23.

    ObjectiveTo examine the effect of mind-body interventions (MBIs) on sleep quality among cancer patients, the moderating effects of the intervention components, subject characteristics, and methodological features of the relationship between MBIs and sleep.Data SourcesElectronic databases, including PubMed, Cochrane Library, PsycINFO, and CINAHL, containing data with English-language restriction recorded up to September 15, 2013 were searched thoroughly using keywords related to various types of MBI and sleep.Study SelectionOf the 114 identified citations, 99 were ineligible. Fifteen studies that followed 1,405 patients with cancer met the inclusion criteria and were analyzed.Data ExtractionThe primary outcome was change in the sleep parameter. Other variables related to components of MBIs, subject characteristics, and methodological features of the studies were also extracted.Data SynthesisThe weighted mean effect size (ES) was -0.43 (95% confidence interval [CI], -0.24 to -0.62) and the long-term effect size (up to 3 months) was -0.29 (95% CI, -0.52 to -0.06). The sensitivity analysis revealed that MBIs had a significant effect on sleep (g = -0.33, P < .001). The moderating effects of components of the intervention, methodological features, subject characteristics, and quality of the studies on the relationship between MBIs and sleep were not found (all P values > .05).ConclusionsThis meta-analysis confirms that the MBIs yielded a medium effect size on sleep quality and the effect was maintained for up to 3 months. The findings support the implementation of MBIs into the multimodal approach to managing sleep quality in patients with cancer.© Copyright 2014 Physicians Postgraduate Press, Inc.

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