• Dig. Dis. Sci. · Aug 2015

    Randomized Controlled Trial Multicenter Study Comparative Study

    Effectiveness of the J-Tip Guidewire for Selective Biliary Cannulation Compared to Conventional Guidewires (The JANGLE Study).

    • Takayoshi Tsuchiya, Takao Itoi, Iruru Maetani, Hiroaki Shigoka, Nobuhito Ikeuchi, Junko Umeda, Atsushi Sofuni, Fumihide Itokawa, Kentaro Ishii, Toshio Kurihara, Shujiro Tsuji, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjyo, Shuntaro Mukai, and Fuminori Moriyasu.
    • Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan, tsuchiya@tokyo-med.ac.jp.
    • Dig. Dis. Sci. 2015 Aug 1;60(8):2502-8.

    BackgroundWire-guided cannulation has become a common biliary cannulation technique worldwide. Different guidewires with various tip shapes and materials have been reportedly used for wire-guided cannulation. However, there are apparently no studies reporting changes in the biliary cannulation rate according to the type of guidewire used.AimsWe evaluated the effectiveness of the J-tip guidewire for biliary cannulation.MethodsWe conducted a prospective, multicenter, controlled study involving patients with a native papilla who required biliary cannulation. We allocated the patients to the J-tip guidewire or angled-tip guidewire groups (groups J and A, respectively). If biliary cannulation was not achieved within 10 min, the GW was changed and cannulation was continued.ResultsGroups J and A consisted of 66 and 65 enrolled patients, respectively. The biliary cannulation rate with a single guidewire for the first 10 min was 84.8 % (56/66) for group J and 80.0 % (52/65) for group A. The final success rate for biliary cannulation was 100 % in both groups. The mean times necessary for biliary cannulation were 285.8 and 267.6 s in group J and group A, respectively. The incidence rates of complications (i.e., all mild pancreatitis) were 3.0 % (2/66) and 6.2 % (4/65) in group J and group A, respectively. The mean amylase concentrations were 168.0 and 297.7 IU/L in group J and group A, respectively. There were no significant differences in any results between both groups.ConclusionThe biliary cannulation rate of the J-tip guidewire was not significantly different from those of standard guidewires.

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