• Yumiko Wakasugi, Nobuyuki Matsuura, and Tatsuya Ichinohe.
• Postgraduate Student, Department of Dental Anesthesiology, Tokyo Dental College, Chiba, Japan. Electronic address: wakasugiyumiko@tdc.ac.jp.
• J. Oral Maxillofac. Surg. 2015 Dec 1; 73 (12): 2294-9.

PurposeThe aim of the present study was to compare the blood loss with remifentanil-based anesthesia with sevoflurane or isoflurane during orthognathic surgery.Patients And MethodsIn this randomized controlled clinical trial, the patients who were scheduled for orthognathic surgery were divided into 2 groups: the sevoflurane (Sevo) group and isoflurane (Iso) group. Anesthesia was maintained using end-tidal concentrations of 1.4% sevoflurane or 0.9% isoflurane. Remifentanil was continuously infused at 0.05 to 0.5 μg/kg/min to maintain the mean blood pressure (MBP) at 60 to 65 mm Hg. The intraoperative blood loss was compared between the 2 groups. The Student t test for unpaired samples was used for statistical analysis. P < .05 was considered statistically significant.ResultsThe study sample included 19 men and 45 women (n = 64). The mean age was 25 years (range 16 to 50). The intraoperative blood loss tended to be greater in the Iso group (n = 32; 4.79 ± 3.22 mL/kg) than in the Sevo group (n = 32; 4.00 ± 1.98 mL/kg). However, the difference between the 2 groups was not significant.ConclusionIn a comparison of intraoperative blood loss during remifentanil-based anesthesia with sevoflurane or isoflurane during orthognathic surgery, no difference was observed between the 2 groups.Copyright © 2015 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

38 keywords...

hide…