• Anaesth Intensive Care · Jun 2001

    Case Reports

    Ventilator-patient dyssynchrony induced by change in ventilation mode.

    • A M Lydon, M Doyle, and M B Donnelly.
    • Department of Anaesthesia and Intensive Care Medicine, Adelaide and Meath Hospital, National Children's Hospital, Tallaght, Dublin, Ireland.
    • Anaesth Intensive Care. 2001 Jun 1;29(3):273-5.

    AbstractPatient-ventilator interactions may be coordinated (synchronous) or uncoordinated (dyssynchronous). Ventilator-patient dyssynchrony increases the work of breathing by imposing a respiratory muscle workload. Respiratory centre output responds to feedback from respiratory muscle loading. Mismatching of respiratory centre output and mechanical assistance results in dyssynchrony. We describe a case of severe patient-ventilator dyssynchrony and hypothesize that dyssynchrony was induced by a change in mode of ventilation from pressure-cycled to volume-cycled ventilation, due to both ventilator settings and by the patient's own respiratory centre adaptation to mechanical ventilation. The causes, management and clinical implications of dyssynchrony are discussed.

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