• Der Urologe. Ausg. A · Nov 1997

    Clinical Trial

    [Tramadol infusion for pain therapy following bladder exstrophy surgery in pediatric wards].

    • N Griessinger, W Rösch, G Schott, and R Sittl.
    • Klinik für Anästhesiologie, Universität Erlangen-Nürnberg.
    • Urologe A. 1997 Nov 1;36(6):552-6.

    AbstractWe investigated in 17 children (mean 7.1 years) the continuous administration of tramadol following augmentation cystoplasty or exstrophy reconstruction. Mean duration of the tramadol administration on the pediatric ward was 3.8 +/- 1.1 days (initial dosage 0.25 mg/kg/per hour, dose adjustment by the nursing staff). Mean tramadol consumption was 0.21 mg/kg/h on day 1 and was reduced to 0.08 mg/kg/per hour on day 4. Median pain score (assessed with ten-step scales) was 5 before treatment and between 2.5 (day 1) and 0.5 (day 5) during therapy. Lowest oxygen saturations (mean) ranged from 93.8% to 95.2%. Three patients (17.6%) suffered from nausea/vomiting on 3 of 64 treatment days (4.7%). Pruritus and extreme sedation did not occur. The continuous administration of tramadol is a simple and safe procedure following major urological surgery in children.

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