• Critical care clinics · Apr 2016

    Review

    Severe Acute Pancreatitis and Necrotizing Pancreatitis.

    • Rahul Maheshwari and Ram M Subramanian.
    • Division of Digestive Diseases, Emory University School of Medicine, 615 Michael Street, Suite 201, Atlanta, GA 30302, USA. Electronic address: rahul.maheshwari@emory.edu.
    • Crit Care Clin. 2016 Apr 1; 32 (2): 279-90.

    AbstractAcute pancreatitis results in nearly 250,000 admissions annually. Acute pancreatitis varies widely in its clinical presentation. Pancreatic necrosis accounts for substantial additional morbidity, with mortality rates remaining as high as 10% to 20% despite advances in critical care. The extent of necrosis correlates well with the incidence of infected necrosis, multiorgan failure, need for pancreatic debridement, and morbidity and mortality. Having established the diagnosis of pancreatic necrosis, goals of appropriately aggressive resuscitation should be established and adhered to in a multidisciplinary approach involving both medical and surgical critical care.Copyright © 2016 Elsevier Inc. All rights reserved.

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