• Paediatric anaesthesia · Sep 2008

    Case Reports

    One hundred times the intended dose of caudal clonidine in three pediatric patients.

    • Cari Meyer and Rachel Cambray.
    • University of Wisconsin School of Medicine and Public Health, Clinical Science Center, Madison, WI 53792-3272, USA. cmeyer@wisc.edu
    • Paediatr Anaesth. 2008 Sep 1;18(9):888-90.

    AbstractWe report three sequential cases in which children received 100 times the intended dose of clonidine in their single shot caudals. Although all experienced excessive somnolence for up to 24 h, none had respiratory depression, oxygen desaturation, supplemental oxygen requirement, or hemodynamic instability. These cases suggest a large margin of safety exists for caudally administered clonidine in healthy children.

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