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Kidney international · Apr 2010
ReviewUrinary liver fatty acid-binding protein: another novel biomarker of acute kidney injury.
- Blaithin A McMahon and Patrick Thomas Murray.
- University College Dublin, Catherine McAuley Centre, Dublin, Ireland.
- Kidney Int. 2010 Apr 1;77(8):657-9.
AbstractLiver fatty acid-binding protein (L-FABP) binds selectively to intracellular free unsaturated fatty acids and lipid peroxidation products during hypoxic tissue injury. Urinary L-FABP is a potential biomarker for the detection and assessment of acute kidney injury (AKI). Ferguson et al. have demonstrated in a cross-sectional study that urinary L-FABP is an excellent biomarker of AKI and may be useful in predicting dialysis-free survival. This study did not assess utility for early diagnosis of AKI.
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