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NeuroRehabilitation · Jan 2012
Case ReportsA case of anti-NMDAR (N-methyl-D-aspartate receptor) encephalitis: a rehabilitation perspective.
- Shuen-Loong Tham and Keng-He Kong.
- Department of Rehabilitation Medicine, Tan Tock Seng Hospital, Singapore.
- NeuroRehabilitation. 2012 Jan 1;30(2):109-12.
AbstractAnti-NMDAR (N-Methyl-D-Aspartate Receptor) Encephalitis is a rare occurring autoimmune disease that is mediated by antibodies against the NR1 subunit of the NMDA receptor. While this condition has a known predilection for young females with ovarian tumors, heightened awareness has led to increasing recognition of this condition in other population groups as well. Afflicted patients typically evolve through a multi-staged course of neurological, behavioral, cognitive and physical deficits. The diverse nature of this condition often necessitates a multi-disciplinary team for management. As the recovery of patients with anti-NMDAR encephalitis is often protracted, the role of the rehabilitation is important particularly beyond its acute stages. We describe a case of anti-NMDAR encephalitis in a 17-year-old girl who presented to our rehabilitation centre for management in the gradual recovery phase of her condition. This case illustrates the multiple challenges faced in the rehabilitation of such a patient.
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