• Anaesthesia · Apr 2012

    Comparative Study

    A comparison of the Nexfin® and transcardiopulmonary thermodilution to estimate cardiac output during coronary artery surgery.

    • M Gruenewald, B Bein, O Broch, M Steinfath, P Meybohm, J Schöttler, A Caliebe, and M Malbrain.
    • Department of Anaesthesiology and Intensive Care Medicine, Christian-Albrechts University, Kiel, Germany. broch@anaesthesie.uni-kiel.de
    • Anaesthesia. 2012 Apr 1;67(4):377-83.

    AbstractThe newly introduced Nexfin(®) device allows analysis of the blood pressure trace produced by a non-invasive finger cuff. We compared the cardiac output derived from the Nexfin and PiCCO, using transcardiopulmonary thermodilution, during cardiac surgery. Forty patients with preserved left ventricular function undergoing elective coronary artery bypass graft surgery were studied after induction of general anaesthesia and until discharge to the intensive care unit. There was a significant correlation between Nexfin and PiCCO before (r(2) = 0.81, p < 0.001) and after (r(2) = 0.56, p < 0.001) cardiopulmonary bypass. Bland-Altman analysis demonstrated the mean bias of Nexfin to be -0.1 (95% limits of agreement -0.6 to +0.5, percentage error 23%) and -0.1 (-0.8 to +0.6, 26%) l.min(-1).m(-2), before and after cardiopulmonary bypass, respectively. After a passive leg-raise was performed, there was also good correlation between the two methods, both before (r(2) = 0.72, p < 0.001) and after (r(2) = 0.76, p < 0.001) cardiopulmonary bypass. We conclude that the Nexfin is a reliable method of measuring cardiac output during and after cardiac surgery.Anaesthesia © 2012 The Association of Anaesthetists of Great Britain and Ireland.

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